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Optical coherence tomography of the human retina
M R Hee1, J A Izatt, E A Swanson
1Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge.
Objective:
To demonstrate optical coherence tomography for high-resolution, noninvasive imaging of the human retina. Optical coherence tomography is a new imaging technique analogous to ultrasound B scan that can provide cross-sectional images of the retina with micrometer-scale resolution.
Design:
Survey optical coherence tomographic examination of the retina, including the macula and optic nerve head in normal human subjects.
Setting:
Research laboratory.
Participants:
Convenience sample of normal human subjects.
Main Outcome Measures:
Correlation of optical coherence retinal tomographs with known normal retinal anatomy.
Results:
Optical coherence tomographs can discriminate the cross-sectional morphologic features of the fovea and optic disc, the layered structure of the retina, and normal anatomic variations in retinal and retinal nerve fiber layer thicknesses with 10-microns depth resolution.
Conclusion:
Optical coherence tomography is a potentially useful technique for high depth resolution, cross-sectional examination of the fundus.