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Neural control of feeding
1Center for Neurobiology and Behavior College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA.
Current Opinion in Neurobiology
|December 1, 1994
Summary
Researchers identified key signals for feeding initiation, including adenosine triphosphate (ATP) and low glucose levels in vertebrates. Progress in invertebrate feeding behavior involves understanding neurotransmitters and developing new modeling tools.
Area of Science:
- Neuroscience
- Animal Behavior
- Molecular Biology
Background:
- Feeding behavior is regulated by complex signaling pathways.
- Understanding these pathways is crucial for addressing metabolic disorders.
Purpose of the Study:
- To review progress in identifying feeding initiation and termination signals.
- To summarize advances in understanding invertebrate feeding mechanisms.
Main Methods:
- Review of existing scientific literature.
- Analysis of signaling molecules and neurotransmitters.
- Development of computational models for feeding networks.
Main Results:
- Adenosine triphosphate (ATP) and decreased glucose levels are implicated in initiating feeding in vertebrates.
- Neurotransmitters and peptide co-transmitters regulating consummatory feeding aspects in invertebrates have been identified.
- New research tools for modeling simple feeding motor program networks are available.
Conclusions:
- Significant progress has been made in elucidating the neurobiological underpinnings of feeding behavior.
- Further research can build upon these findings to explore therapeutic interventions for feeding disorders.