[Infraclinical breast carcinoma]

Area of Science:

• Oncology
• Radiology
• Surgical Pathology

Background:

• Early breast cancer detection is crucial for reducing disease morbidity and mortality.
• Mammography offers high sensitivity for detecting infraclinical tumors.
• Clinically occult malignant tumors, including ductal carcinoma in situ and small invasive cancers, pose diagnostic challenges.

Purpose of the Study:

• To highlight the importance of early breast cancer detection.
• To review the roles of various imaging modalities in identifying occult breast tumors.
• To emphasize the necessity of preoperative marking and intraoperative verification for suspected breast lesions.

Main Methods:

• Mammography as the primary tool for detecting infraclinical tumors.
• Ultrasonography and MR mammography as complementary imaging techniques.
• Preoperative marking using hookwire or carbon for suspected lesions.
• Intraoperative specimen radiography for surgical site verification.

Main Results:

• Mammography demonstrates high sensitivity in detecting early-stage breast cancers.
• Ultrasonography and MR mammography provide valuable complementary information.
• Preoperative marking facilitates precise localization and removal of non-palpable lesions.
• Intraoperative specimen radiography confirms complete tumor excision.

Conclusions:

• Early detection through mammography is key to reducing breast cancer mortality.
• A multimodal imaging approach enhances the detection of occult breast cancers.
• Standardized preoperative marking and intraoperative specimen radiography ensure effective surgical management.