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Alzheimer patients show a sensitivity decrement over time on a tonic alertness task
M Brazzelli1, G Cocchini, S Della Sala
1Neurology Department, Clinica del Lavoro Foundation, Medical Centre of Veruno (Novara), Italy.
Journal of Clinical and Experimental Neuropsychology
|December 1, 1994
Abstract:
Tonic alertness was investigated in Alzheimer patients and normal elderly subjects. Sensitivity and criterion shifts were investigated across 45 min of continuous testing using a high event rate test with very low target probability. Alzheimer patients showed a significant sensitivity decrement over time that was unrelated to dementia severity. These results suggest that tonic alertness is impaired by Alzheimer's disease even in its early stages.