Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Neurosyphilis

D N Scheck1, E W Hook

  • 1University of Alabama School of Medicine, Birmingham.

Infectious Disease Clinics of North America
|December 1, 1994
PubMed
Summary
This summary is machine-generated.

Central nervous system invasion by Treponema pallidum is common in syphilis patients. Early detection of asymptomatic neurosyphilis is crucial for preventing severe neurological complications.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pneumocystis pneumonia in hospitalized patients: a detailed examination of symptoms, management, and outcomes in human immunodeficiency virus (HIV)-infected and HIV-uninfected persons.

Transplant infectious disease : an official journal of the Transplantation Society·2012
Same author

Risk behaviours in HIV-positive men who have sex with men participating in an intervention in a primary care setting.

International journal of STD & AIDS·2009
Same author

High-risk behaviours among juvenile prison inmates in Pakistan.

Public health·2009
Same author

Characteristics of the m2000 automated sample preparation and multiplex real-time PCR system for detection of Chlamydia trachomatis and Neisseria gonorrhoeae.

Journal of clinical microbiology·2007
Same author

A multi-centre evaluation of nine rapid, point-of-care syphilis tests using archived sera.

Sexually transmitted infections·2006
Same author

Historical correlates of genital herpes simplex virus type 2 infection in men attending an STD clinic.

Sexually transmitted infections·2005

Area of Science:

  • Neurology
  • Infectious Diseases
  • Microbiology

Background:

  • Treponema pallidum frequently invades the central nervous system (CNS) in syphilis patients.
  • Asymptomatic neurosyphilis, indicated by cerebrospinal fluid abnormalities, increases the risk of clinical neurosyphilis.
  • Clinical neurosyphilis can manifest anytime during untreated syphilis, leading to significant patient morbidity.

Purpose of the Study:

  • To highlight the prevalence and risks associated with central nervous system invasion in syphilis.
  • To emphasize the importance of recognizing asymptomatic neurosyphilis.
  • To underscore the diagnostic challenges and clinical approach to neurosyphilis.

Main Methods:

  • Review of existing literature on neurosyphilis.

Related Experiment Videos

  • Analysis of diagnostic criteria and clinical presentations.
  • Discussion of the implications of CNS invasion by Treponema pallidum.

    • Main Results:

    • Central nervous system invasion by Treponema pallidum is a common occurrence in syphilis.
    • Asymptomatic neurosyphilis is a precursor to symptomatic neurosyphilis syndromes.
    • Clinical neurosyphilis development is unpredictable and can cause severe long-term health issues.

    Conclusions:

    • Effective diagnosis and management of neurosyphilis require a comprehensive approach.
    • Clinicians must integrate clinical findings with laboratory data for accurate neurosyphilis diagnosis.
    • Understanding the natural history of Treponema pallidum CNS invasion is vital for patient outcomes.