Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Fibrous metaphyseal defects]

P Ritschl1, H Wiesauer, P Krepler

  • 1Orthopädisches Krankenhaus Gersthof, I. Abteilung, Wien.

Der Orthopade
|February 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Authors' Reply: Perforated Diverticulitis with Generalized Peritonitis: Low Stoma Rate Using a "Damage Control Strategy".

World journal of surgery·2019
Same author

Reply to the Letter to the Editor of S. Shahsavari et al. concerning "Predicting medical complications in spine surgery: evaluation of a novel online risk calculator" by M. F. Kasparek et al. (Eur Spine J: doi: 10.1007/s00586-018-5707-9).

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·2018
Same author

Perforated Diverticulitis with Generalized Peritonitis: Low Stoma Rate Using a "Damage Control Strategy".

World journal of surgery·2018
Same author

Damage control surgery in perforated diverticulitis: ongoing peritonitis at second surgery predicts a worse outcome.

International journal of colorectal disease·2018
Same author

[Patellar bone deficiency in revision total knee arthroplasty].

Der Orthopade·2016
Same author

Patient-related factors influence stiffness of the soft tissue complex during intraoperative gap balancing in cruciate-retaining total knee arthroplasty.

Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA·2015
Same journal

[Fast-track hip and knee joint arthroplasty].

Der Orthopade·2022
Same journal

[Outpatient care through cross-sector prehabilitation and rehabilitation concepts in outpatient hip and knee arthroplasty].

Der Orthopade·2022
Same journal

[Preoperative management in fast-track arthroplasty].

Der Orthopade·2022
Same journal

[Perioperative management in fast-track arthroplasty].

Der Orthopade·2022
Same journal

[Pain therapy and anaesthesiological procedures in fast-track arthroplasty].

Der Orthopade·2022
Same journal

[Discharge readiness versus discharge-Results of the PROMISE study].

Der Orthopade·2022
See all related articles

Fibrous metaphyseal defects (FMD), a type of bone lesion in children, are linked to specific tendon insertions near growth plates. Pathological examination reveals fibroblastic tissue replacing normal bone at these sites.

Area of Science:

  • Orthopedic Pathology
  • Pediatric Bone Lesions
  • Skeletal Development

Background:

  • Fibrous metaphyseal defects (FMD) are classified as tumor-like bone lesions in children and adolescents.
  • These defects occur at specific locations on long bones, with proximity to the epiphyseal line varying by age.
  • The orientation of FMDs suggests a connection to tendon or ligamentous structures inserting at the growth plate.

Purpose of the Study:

  • To investigate the pathogenetic role of tendon insertions in the development of fibrous metaphyseal defects.
  • To examine the anatomical relationship between specific tendon insertions and the occurrence of FMDs.
  • To analyze the histological changes associated with FMDs at tendon insertion sites.

Main Methods:

  • Autopsy examination of 152 long tubular bones from individuals with open epiphyseal growth plates.

Related Experiment Videos

  • Detailed analysis of tendons and ligamentous structures inserting into the perichondrium of the epiphyseal plate cartilage.
  • Pathomorphological assessment of tissue changes within identified tendon insertion areas (Ranvier's nodes).

    • Main Results:

    • The study identified specific tendon insertion sites (Ranvier's nodes) associated with FMDs.
    • Pathomorphological examination revealed that normal medullary bone tissue is replaced by fibroblastic tissue at these sites.
    • These findings support a causal relationship between tendon insertions and FMD pathogenesis.

    Conclusions:

    • Tendon insertions into the perichondrium of the epiphyseal plate play a significant role in the etiopathogenesis of fibrous metaphyseal defects.
    • The histological changes observed confirm the displacement of normal bone by fibroblastic tissue at these specific locations.
    • Further discussion encompasses the radiological, clinical, and histological features, as well as the prognosis of FMDs.