Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Angiosarcoma developing from chronic pyothorax

K Aozasa1, N Naka, Y Tomita

  • 1Department of Pathology, Osaka University School of Medicine, Japan.

Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc
|December 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Discovery of cockroach specimens of the genus Squamoptera (Ectobiidae: Pseudophyllodromiinae) from Okinawa, Japan, showing wing polymorphism.

Tropical biomedicine·2021
Same author

Ecological succession of the microbial communities of an air-conditioning cooling coil in the tropics.

Indoor air·2016
Same author

Species clarification of Ogasawara cockroaches which inhabit Japan.

Tropical biomedicine·2015
Same author

Are tyrosine residues involved in the photoconversion of the water-soluble chlorophyll-binding protein of Chenopodium album?

Plant biology (Stuttgart, Germany)·2014
Same author

Lymphokine-activated killer cell activity Characteristics of effector cells and their progenitors in blood and spleen.

Immunology today·2014
Same author

Images created in a model eye during simulated cataract surgery can be the basis for images perceived by patients during cataract surgery.

Eye (London, England)·2014

Chronic pyothorax, a long-standing pleural inflammation, significantly increases the risk of developing angiosarcoma (AS). This study confirms chronic tuberculous pyothorax as a key etiological factor for this rare cancer.

Area of Science:

  • Oncology
  • Pathology
  • Epidemiology

Background:

  • Long-standing pleural inflammation is a suspected etiological factor for pleural soft-tissue sarcomas.
  • Malignant fibrous histiocytoma and angiosarcoma (AS) are specific types of pleural sarcomas.
  • The etiological role of chronic pyothorax in AS development requires further investigation.

Purpose of the Study:

  • To investigate the etiological importance of chronic pyothorax in the development of pleural angiosarcoma (AS).
  • To assess the incidence and characteristics of pyothorax-associated AS in Japan.

Main Methods:

  • A nationwide study of AS cases in Japan was conducted.
  • Histological and clinical findings of 99 AS cases were reviewed.
  • Data on chronic pyothorax history and tumor characteristics were analyzed.

Related Experiment Videos

Main Results:

  • Six (6%) of 99 AS cases were identified as chronic pyothorax-associated.
  • An additional three previously reported cases were included, totaling nine patients.
  • All patients had a history of chronic tuberculous pyothorax (15-40 years).
  • Tumor histology revealed irregular vascular channels with epithelioid tumor cells.
  • The incidence rate of pyothorax-associated AS among chronic pyothorax patients was 0.036 per 100 patients, over 3600-fold higher than in the general population.

Conclusions:

  • Chronic tuberculous pyothorax is a significant etiological factor for angiosarcoma development.
  • Pleural inflammation associated with chronic pyothorax increases the risk of AS.