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[Isolated lung transplantation]

W Weder¹, R Speich, A Boehler

¹Departement Chirurgie, Universitätsspital Zürich.

Schweizerische Medizinische Wochenschrift

|March 11, 1995

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Lung transplantation has advanced significantly, becoming a viable treatment for end-stage lung disease. Improved techniques and management have led to higher survival rates for lung transplant recipients.

Area of Science:

Cardiovascular and Respiratory System Sciences
Surgical Sciences
Immunology

Context:

Lung transplantation has evolved from an experimental procedure to a standard therapy over the past decade.
This advancement is crucial for patients suffering from end-stage pulmonary or pulmonary-vascular diseases.
Significant progress has been observed in the global and national contexts of lung transplantation.

Purpose:

To review the advancements in lung transplantation over the last 10 years.
To discuss the key factors contributing to the improved outcomes in lung transplantation.
To present the indications, techniques, management, and results of lung transplantation.

Summary:

Single and bilateral lung transplantation has seen remarkable progress, driven by refined patient selection, surgical techniques, organ preservation, and perioperative care.

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Advances in immunosuppressive and anti-infective therapies have further enhanced patient outcomes.

Worldwide, over 3000 lung transplantations have been performed since 1983, with 1- and 3-year survival rates of 70-90% and 60-70%, respectively.

In Switzerland, since 1992, more than 80% 1-year survival has been achieved in 41 lung transplantations.

Impact:

Lung transplantation is now a well-established and effective treatment option for severe lung conditions.
Improved survival rates demonstrate the success of current medical and surgical strategies.
The discussion of indications, techniques, and results provides valuable insights for clinicians and researchers in the field.