Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) in Liberia

Rosai-Dorfman disease is rare. Two patients, one with nodal and another with extra-nodal disease, are presented. The clinical and pathological features of the two cases are typical of the disease. Because the disease can present with a diverse picture, it can be easily misdiagnosed. It is therefore suggested that physicians and paediatricians should exercise more vigilance in order to detect more cases, particularly in the early stages, for better understanding of the natural history of this disease about which little is known at this stage.