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[Cancer of the penis. 1989]

J Auvert1, L Roubach

  • 1Expansion Scientifique Française, Paris.

Annales D'Urologie
|January 1, 1994
PubMed
Summary

Penile cancer, a rare male cancer, is highly lymphophilic, with prognosis depending on lymphatic spread. Diagnosis involves biopsy, and treatment ranges from surgery to chemotherapy based on cancer stage.

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Area of Science:

  • Oncology
  • Urology

Background:

  • Penile cancer is a rare male genital tract tumor, comprising 1% of male cancers.
  • It exhibits high lymphophilicity, complicating diagnosis and treatment of both primary tumors and lymph nodes.

Discussion:

  • Prognosis is strongly correlated with the extent of lymphatic spread.
  • The cancer predominantly affects uncircumcised men with poor personal hygiene.
  • Diagnosis relies on biopsy of persistent glans lesions.

Key Insights:

  • Treatment necessitates complete prepuce removal.
  • Early-stage, noninvasive cancers may be treated with radioactive iridium wire.
  • Inguinal lymph node biopsy is indicated for palpable nodes, with extensive dissection required for lymph node involvement.

Outlook:

  • Advanced stages (T3) with corpora cavernosa invasion require extensive penile amputation and lymph node dissection.
  • Unresectable lymph nodes or metastases necessitate combination chemotherapy (MTX-cisplatin-bleomycin).
  • Adjuvant irradiation is reserved for tumors extending beyond the lymph node capsule.

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