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Massive dextromethorphan ingestion and abuse

T R Wolfe1, E M Caravati

  • 1Division of Emergency Medicine, University of Utah School of Medicine, Salt Lake City.

The American Journal of Emergency Medicine
|March 1, 1995
PubMed
Summary
This summary is machine-generated.

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This case study details a 23-year-old man with extreme dextromethorphan (DXM) abuse, consuming record-high doses daily for an extended period. It highlights the severe toxicity and addiction potential associated with chronic DXM intoxication.

Area of Science:

  • Pharmacology
  • Toxicology
  • Addiction Medicine

Background:

  • Dextromethorphan (DXM) is an over-the-counter cough suppressant.
  • Recreational abuse of DXM can lead to significant health risks.
  • Chronic high-dose DXM use is not well-documented in medical literature.

Observation:

  • A case of a 23-year-old male with acute and chronic dextromethorphan intoxication is presented.
  • The patient reported the highest daily dose and longest duration of DXM consumption ever documented.
  • Symptoms and clinical course of severe DXM toxicity were observed.

Findings:

  • The case illustrates the extreme abuse potential of dextromethorphan.
  • High-dose, long-term DXM use can result in severe intoxication.

Related Experiment Videos

  • This report documents unprecedented levels of DXM consumption.

    • Implications:

    • Understanding the toxicity profile of high-dose dextromethorphan is crucial for clinicians.
    • This case underscores the need for awareness regarding the abuse potential of common medications.
    • Further research into the long-term effects and management of DXM addiction is warranted.