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Updated: Jul 25, 2026

5/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat
Published on: July 3, 2013
[Disorders of oxidation-reduction processes in nephrotic syndrome]
Abstract:
Reduction capacity of the blood and its fractions was studied by potentiometry in 68 patients with the nephrotic syndrome. The type of renal injury was identified by kidney biopsy in all the patients. Control group consisted of 30 donors. Changes of blood reduction capacity were detected in all the patients with the nephrotic syndrome in comparison with the controls. A correlation could be traced between blood reduction capacity and functional compensation of the nephrotic syndrome. Disordered redox equilibrium was not associated in patients with the nephrotic syndrome with increased levels of lipid peroxidation products. The method used to assess reduction capacity is highly informative, rapid, and simple.
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