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MRI of radiation-induced prostate sarcoma
H V Nghiem1, F G Sommer, J C Moretto
1Department of Radiology, University of Washington School of Medicine, Seattle 98195.
Clinical Imaging
|January 1, 1995
Summary
Radiation-induced sarcoma of the prostate can occur after pelvic radiation therapy for seminoma. This case highlights the importance of considering radiation-induced tumors in patients with prior pelvic radiation history.
Area of Science:
- Oncology
- Radiology
- Pathology
Background:
- Pelvic radiation therapy is a common treatment for seminoma.
- Secondary malignancies can arise after radiation exposure.
Observation:
- A patient treated for seminoma developed a prostatic tumor with specific MRI characteristics.
- High signal intensity on T2-weighted MRI and low-signal-intensity pelvic sidewall tissue were noted.
Findings:
- Surgical pathology confirmed a radiation-induced sarcoma of the prostate.
- Associated extraprostatic tissue was identified as postradiation fibrosis.
Implications:
- This case underscores the potential for radiation-induced sarcomas following seminoma treatment.
- Radiologists and oncologists should consider this diagnosis in patients with relevant history and imaging findings.