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Ovarian and endometrial cancers
1Department of Public Health and Primary Care, University of Oxford, Radcliffe Infirmary.
Cancer Surveys
|January 1, 1994
Summary
Endometrial cancer mortality declined, but incidence remained stable. Ovarian cancer mortality decreased in younger women, but increased in older women, potentially linked to oral contraceptive use.
Area of Science:
- Epidemiology
- Gynecologic Oncology
- Public Health
Background:
- Cancer epidemiology studies track disease trends over time.
- Understanding incidence and mortality patterns is crucial for public health interventions.
- Long-term data analysis provides insights into disease progression and risk factors.
Purpose of the Study:
- To analyze trends in endometrial and ovarian cancer incidence and mortality.
- To compare these trends across England and Wales with other selected countries.
- To explore potential explanations for observed epidemiological patterns.
Main Methods:
- Descriptive epidemiological analysis of cancer registry data.
- Examination of incidence and mortality rates from 1950-1991 (England & Wales) and 1955-1985 (international).
- Comparison of trends across different age groups and geographic regions.
Main Results:
- Endometrial cancer: Declining mortality but stable incidence observed in England & Wales and internationally.
- Ovarian cancer: Declining mortality in women under 55, rising in women over 55 in England & Wales.
- International ovarian cancer trends showed varied patterns, with declining mortality in younger women in several countries.
Conclusions:
- Endometrial cancer trends are difficult to explain by known risk factors.
- Ovarian cancer mortality trends in younger women may be influenced by combined oral contraceptive use.
- Further research is needed to elucidate the complex factors affecting gynecologic cancer trends.
Keywords:
BiologyCancerContraceptionContraceptive Methods--beneficial effectsCorrelation StudiesDemographic FactorsDiseasesEndometrial CancerFamily PlanningHormone Replacement TherapyLiterature ReviewMortalityMortality Decline--determinantsNeoplasmsOral Contraceptives, Combined--beneficial effectsOral Contraceptives--beneficial effectsOvarian CancerPopulationPopulation DynamicsResearch MethodologyRisk FactorsStatistical StudiesStudiesTreatmentWorld