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Prostate cancer

A S Whittemore1

  • 1Stanford University School of Medicine, Department of Health, Research and Policy, California 94305.

Cancer Surveys
|January 1, 1994
PubMed
Summary
This summary is machine-generated.

Prostate cancer incidence and mortality increased globally from 1968-1987, possibly due to enhanced detection. Rising healthcare costs for prostate cancer may not reduce overall disease burden.

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Area of Science:

  • Oncology
  • Epidemiology
  • Public Health

Background:

  • Prostate cancer is a significant global health concern.
  • Understanding trends in incidence and mortality is crucial for resource allocation and public health strategies.

Purpose of the Study:

  • To examine trends in prostate cancer incidence and mortality across England, Italy, Japan, Sweden, and the USA.
  • To investigate potential factors contributing to observed trends, including detection rates and death certification practices.
  • To analyze international and interethnic variations in prostate cancer epidemiology.

Main Methods:

  • Analysis of prostate cancer incidence and mortality data from selected countries over the period 1968-1987.
  • Comparison of trends across different populations and ethnic groups.

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  • Consideration of the impact of diagnostic advancements and death certification practices on reported statistics.

    • Main Results:

    • Prostate cancer incidence rose in all studied populations between 1968-1972 and 1983-1987, with increased detection rates likely contributing.
    • Mortality also increased in most populations during the same period, with potential contributions from both real disease progression and altered death certification.
    • Significant international and interethnic disparities in both incidence and mortality were observed across all time periods.

    Conclusions:

    • The observed temporal rise in prostate cancer incidence suggests increasing global healthcare costs associated with the disease.
    • Increased detection of localized, asymptomatic prostate cancer may inflate incidence rates without a proportional decrease in morbidity or mortality.
    • International differences in detection rates complicate the interpretation of incidence data, while mortality differences are unlikely solely due to certification practices.