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Antidepressant principles of Valeriana fauriei roots
Y Oshima1, S Matsuoka, Y Ohizumi
1Pharmaceutical Institute, Tohoku University, Sendai, Japan.
Chemical & Pharmaceutical Bulletin
|January 1, 1995
Abstract:
A methanol extract of the roots of Valeriana fauriei (Valerianaceae), exhibited antidepressant activity in mice. The extract was fractioned, monitored by the activity, to afford alpha-kessyl alcohol as an active principle. The antidepressant activity of some guaiane and valerane types of sesquiterpenoids in the active fraction was also evaluated.