[Growth and spore formation of Bacillus subtilis in periodic and dialysis cultured: experiment and modeling]

The transition of bacilli to maintenance state in dialysis culture was revealed. The maintenance state is characterized by the lack of growth and spore formation. The experimental results are satisfactorily described by a modification of the synthetic chemostat model. As a results of model realization it was supposed that maintenance state of bacilli was connected with synthesis of autoinhibitor and initiation of spore formation.