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Updated: Sep 30, 2026

Method of Direct Segmental Intra-hepatic Delivery Using a Rat Liver Hilar Clamp Model
Published on: April 2, 2017
[Major liver injury. Role of preoperative transcutaneous endoluminal aortic clamping]
Insights
Severe liver contusions have a poor prognosis. Percutaneous intra-aortic balloon occlusion and liver vascular exclusion improved survival rates in patients with major liver injury, reducing intra-operative deaths.
Area of Science:
- Trauma surgery
- Vascular surgery
- Hepatobiliary surgery
Context:
- Severe liver contusions (Type V) present significant management challenges.
- Exsanguination poses a risk of cardiac arrest during surgical intervention.
- Limited effective strategies exist for managing major liver trauma.
Purpose:
- To evaluate the efficacy of percutaneous intra-aortic balloon occlusion combined with surgical hepatic vascular exclusion for severe liver injuries.
- To assess the impact of this combined approach on intra-operative mortality and patient survival.
Summary:
- Three patients with severe liver contusions underwent treatment using percutaneous intra-aortic balloon occlusion and surgical hepatic vascular exclusion.
- Aortic occlusion was achieved via a femoral catheter, followed by surgical vascular exclusion of the liver after hemodynamic stabilization.
- Two of the three patients survived the procedure, with one mortality attributed to associated lung trauma.
Impact:
- Percutaneous intra-aortic balloon occlusion offers a minimally invasive method to control hemorrhage in major liver trauma.
- This technique facilitates safer surgical conditions for liver resection in critically injured patients.
- The combined approach shows potential to improve survival outcomes for severe liver contusions by reducing intra-operative deaths.
Abstract:
Severe contusion of the liver (type V in the Moore and Flint classification) still has a very poor prognosis. Exsanguination may lead to cardiac arrest when the abdomen is opened. Three patients with major liver injury were treated after percutaneous intra-aortic balloon occlusion and complete vascular exclusion of the liver. Two patients survived and one died due to complications resulting from lung trauma. The aorta was occluded with a balloon catheter inserted via the femoral route. The hepatic vascular exclusion was performed surgically after resuscitation had reestablished a satisfactory haemodynamic situation. Liver resection could then be performed under safe conditions. Aortic occlusion is a simple procedure with minimal disadvantages which could improve prognosis of major liver contusion by reducing the rate of intra-operative death.
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