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[Resistant pneumococci in pediatrics: therapeutic implications]

E Bingen1, A Bourrillon

  • 1Laboratoire de Microbiologie, Hôpital Robert Debré, Paris.

Presse Medicale (Paris, France : 1983)
|January 14, 1995
PubMed
Summary
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Pneumococci infections are common in French children, with increasing antibiotic resistance. Amoxicillin and other antibiotics are recommended for treatment, especially for otitis and meningitis.

Area of Science:

  • Bacteriology
  • Infectious Diseases
  • Pediatrics

Context:

  • Pneumococci are a leading cause of pediatric pneumonia and bacteremia in France.
  • They are also a significant cause of conjunctivitis, otitis, and meningitis in young children.
  • Increasing antibiotic resistance, particularly to beta-lactamines, macrolides, and tetracyclines, complicates treatment.

Purpose:

  • To review the epidemiology of pneumococcal infections in children in France.
  • To highlight the growing problem of antibiotic resistance in Streptococcus pneumoniae strains.
  • To propose therapeutic strategies for common pediatric pneumococcal infections, considering resistance patterns.

Summary:

  • Pneumococci are a major pediatric pathogen in France, responsible for pneumonia, bacteremia, otitis, and meningitis.

Related Experiment Videos

  • High rates of resistance to penicillin, macrolides, tetracyclines, and other antibiotics are reported.
  • Therapeutic strategies must account for local resistance prevalence, recommending amoxicillin, pristinamycin, or ceftriaxone for specific infections like otitis and meningitis.
  • Impact:

    • The study underscores the challenge of treating pneumococcal infections due to widespread antibiotic resistance.
    • It emphasizes the need for probabilistic treatment approaches based on local resistance data.
    • Recommendations for amoxicillin and other antibiotics aim to guide clinicians in managing pediatric pneumococcal infections effectively.