Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Antibiotherapy in the past, present and future]

A Bryskier1

  • 1Laboratoire de Microbiologie, Centre Hospitalier Victor Dupouy, Argenteuil.

Presse Medicale (Paris, France : 1983)
|January 14, 1995
PubMed
Summary

The antibiotic era, beginning in 1941, yielded penicillin and erythromycin. However, the rise of resistant bacteria necessitates new anti-infective strategies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Antibacterial drug discovery and development--third international summit. 8-9 March 1999, Princeton, NJ, USA.

IDrugs : the investigational drugs journal·2005
Same author

Novelties in the field of fluoroquinolones.

Expert opinion on investigational drugs·2005
Same author

New research in macrolides and ketolides since 1997.

Expert opinion on investigational drugs·2005
Same author

Dual beta-lactam-fluoroquinolone compounds: a novel approach to antibacterial treatment.

Expert opinion on investigational drugs·2005
Same author

Novelties in the field of macrolides.

Expert opinion on investigational drugs·2005
Same author

Mechanisms of macrolide resistance in clinical pneumococcal isolates in a university hospital, Ankara, Turkey.

Journal of chemotherapy (Florence, Italy)·2005

Area of Science:

  • Microbiology
  • Pharmacology
  • Medicinal Chemistry

Context:

  • The discovery of antibiotics revolutionized medicine starting in 1941.
  • Antibiotics derived from fermentation (penicillin, erythromycin) and synthetic routes (quinolones, etc.) have been developed.
  • The emergence of antibiotic-resistant bacteria poses a significant challenge to infectious disease treatment.

Purpose:

  • To review the historical development of antibiotics.
  • To highlight the ongoing challenge of antimicrobial resistance.
  • To emphasize the need for novel anti-infective therapies.

Summary:

  • The antibiotic era commenced in 1941 with natural products like penicillin and erythromycin.
  • Synthetic antibacterial agents, including quinolones and nitroheterocycles, were subsequently developed.
  • Despite therapeutic advances, the parallel emergence of resistant bacterial strains demands new approaches to anti-infective therapy.

Impact:

  • Understanding the historical context of antibiotic development is crucial.
  • Antimicrobial resistance necessitates continuous innovation in drug discovery.
  • Future research must focus on new compounds and therapeutic concepts to combat infections effectively.

Related Experiment Videos