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[Pancreas transplantation. A 10-year material]
I B Brekke1, O Bentdal, P Pfeffer
1Kirurgisk avdeling B, Rikshospitalet, Oslo.
Summary
This study reviews 10 years of pancreas transplantation in Oslo. Simultaneous pancreas-kidney transplants since 1991 show improved graft survival rates for diabetic patients.
Area of Science:
- Nephrology
- Transplantation Surgery
- Endocrinology
Context:
- Oslo's pancreas transplant program began in 1983.
- Initial procedures included pancreas transplantation alone (PTA) and pancreas after kidney (PAK).
- Surgical techniques evolved from duct-occluded segmental grafts to pancreaticoduodenal technique with bladder drainage.
Purpose:
- To review a decade of pancreas transplantation experience.
- To evaluate the evolution of surgical techniques and outcomes.
- To identify optimal strategies for pancreas transplant success.
Summary:
- A total of 100 pancreas transplants were performed, with 14 as PTA or PAK.
- Lower graft survival rates in PAK and PTA cases led to a shift in strategy.
- Since 1991, all pancreas transplants are performed simultaneously with kidney transplants.
Impact:
- Simultaneous pancreas-kidney transplantation demonstrates improved outcomes.
- Achieved one-year survival rates of 82% for kidney, 83% for pancreas, and 93% for patients.
- Established a consistent pancreas transplant rate of ten per year.