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[Refractory hypertension]

I Os1, I K Eide, A S Westheim

  • 1Nyremedisinsk avdeling, Ullevål sykehus, Oslo.

Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke
|February 28, 1995
PubMed
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Resistant hypertension, defined as blood pressure uncontrolled by three or more medications, often involves plasma volume expansion. Improving physician-patient relationships and patient education are key to managing this challenging condition.

Area of Science:

  • Cardiology
  • General Practice
  • Pharmacology

Context:

  • Resistant hypertension is a prevalent clinical challenge.
  • Defined as inadequate blood pressure control despite multiple antihypertensive agents.
  • Requires careful consideration of underlying mechanisms and patient factors.

Purpose:

  • To highlight the significance of plasma volume expansion in resistant hypertension.
  • To emphasize the role of patient adherence and physician-patient relationships.
  • To guide clinicians in managing difficult-to-treat hypertension.

Summary:

  • Resistant hypertension necessitates recognizing plasma volume expansion as a key factor.
  • White-coat hypertension and medication non-compliance are common confounding issues.

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  • Effective management hinges on addressing these factors and fostering patient adherence.

    • Impact:

    • Improved understanding of resistant hypertension mechanisms.
    • Enhanced strategies for optimizing antihypertensive therapy.
    • Better patient outcomes through improved medication adherence and clinical management.