[The clinical evaluation of the antidepressive activity of fluoxetine]

The authors studied therapeutic properties of fluoxetine in the treatment of 100 patients with endogenous depressions. The drug was introduced during 6 weeks in a daily dose 20 mg. On the basis of the analysis of its clinical action and adverse reactions, fluoxetine belonging to the class of antidepressants has been ascertained. A prevalence of thymoleptic and stimulating components in its action, equal by their degree of expressivity and a smaller degree of anxiolytic effect have been demonstrated. Differentiated indications to fluoxetine prescription, its predilection in the therapy of apatho-adynamic and melancholic depressions and the feasibility of its use in inpatient conditions are discussed.