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Related Experiment Videos

Perinatal outcome after in vitro fertilisation

K Petersen1, P J Hornnes, S Ellingsen

  • 1Department of Obstetrics and Gynecology, Rigshospitalet, University of Copenhagen, Denmark.

Acta Obstetricia Et Gynecologica Scandinavica
|February 1, 1995
PubMed
Summary

In vitro fertilisation (IVF) singleton deliveries resulted in lower infant birth weights compared to other infertility treatments. However, no significant differences were observed in pregnancy complications or multiple births.

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Area of Science:

  • Reproductive Medicine
  • Perinatology
  • Obstetrics

Background:

  • In vitro fertilisation (IVF) is a widely used assisted reproductive technology.
  • Understanding the perinatal outcomes of IVF pregnancies is crucial for clinical practice.

Purpose of the Study:

  • To compare pregnancy complications and infant birth weight between IVF and non-IVF pregnancies.
  • To investigate potential differences in singleton versus multiple gestations.

Main Methods:

  • Prospective comparison of 90 IVF pregnancies with control groups (non-IVF infertility and normally fertile women).
  • Data collected on third-trimester complications, fetal karyotypes, malformations, labor onset, gestational age, and birth weight.
  • Analysis stratified by singleton and multiple gestations.

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Main Results:

  • No significant differences in third-trimester complications, abnormal karyotypes, or malformations between IVF and control groups.
  • Singleton deliveries after IVF showed significantly lower birth weights compared to controls (median 3145g vs 3399g).
  • Birth weights for multiple gestations were similar between IVF and control groups.

Conclusions:

  • Singleton infants born after IVF have lower birth weights than those from other infertility treatments.
  • The underlying causes for the reduced birth weight in singleton IVF deliveries remain unclear.
  • IVF does not appear to increase risks for pregnancy complications or malformations compared to controls.