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Class II major histocompatibility complex molecule expression on murine eosinophils activated in vivo by Brugia
S D Mawhorter1, E Pearlman, J W Kazura
1Division of Geographic Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106-4984.
Infection and Immunity
|December 1, 1993
Abstract:
The Th-2 response to microfilariae of Brugia malayi in BALB/c mice is associated with peritoneal eosinophilia. These eosinophils had an activated hypodense phenotype in vivo and expressed high levels of the class II major histocompatibility complex (MHC). Interleukin 4 up-regulated the class II MHC, whereas gamma interferon inhibited class II MHC expression on eosinophils.