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Related Experiment Videos

Embryologic concepts in the APUD system

R Delcore1, S R Friesen

  • 1Department of Surgery, University of Kansas Medical Center, Kansas City 66160-7309.

Seminars in Surgical Oncology
|September 1, 1993
PubMed
Summary
This summary is machine-generated.

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This chapter explores the embryologic origins of the amine precursor uptake and decarboxylation (APUD) system, revealing its role in the neuroendocrine system. Understanding APUD embryology clarifies the interplay between neural and endocrine functions in various syndromes.

Area of Science:

  • Neuroendocrinology
  • Developmental Biology
  • Cell Biology

Background:

  • The neuroendocrine system integrates neural and endocrine functions for homeostasis.
  • The amine precursor uptake and decarboxylation (APUD) system is central to understanding neuroendocrine development.
  • APUD system embryology provides insights into the origins of diverse syndromes.

Purpose of the Study:

  • To review the embryologic concepts of the APUD system.
  • To clarify the historical and cytochemical developments in APUD system theories.
  • To explain the neuroendocrine system as the third division of the nervous system.

Main Methods:

  • Chronological review of evolving theories on APUD system embryology.
  • Integration of historical developments and cytochemical discoveries.

Related Experiment Videos

  • Examination of new investigative tools and their impact on understanding.

    • Main Results:

    • Theories on APUD system embryology have evolved significantly over time.
    • New data continually modifies and develops earlier theories.
    • The neuroendocrine system's role as a link between autonomic nerves and endocrine cells is highlighted.

    Conclusions:

    • Embryologic understanding of the APUD system is crucial for comprehending neuroendocrine regulation.
    • The interplay of neural and endocrine actions in syndromes is better understood through APUD system origins.
    • Ongoing research and new technologies continue to refine theories on neuroendocrine development.