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[Hematologic remission and disappearance of hemolytic anemia in chronic lymphocytic leukemia after therapy with
B Piatkowska-Jakubas1, A B Skotnicki
1Kliniki Hematologii Collegium Medicum UJ, Krakowie.
Acta Haematologica Polonica
|January 1, 1993
Abstract:
A 62 yr old patient with CLL (Binet C) with severe hemolytic anemia, resistant to conventional immunosuppressive treatment (cyclophosphamide, azathioprine, steroids) had been treated with two cycles of 2-CDA. The therapy resulted in the decrease of leukocyte count (even below 1000/microliters), with subsequent recovery of fairly normal granulopoiesis, eradication of lymphocyte infiltration of the bone marrow, and inhibition of the autoimmune phenomena.