[Neurotransmitter-receptor-imaging]
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M Cordes1, J Hierholzer, K Nikolai-Beyer
1Strahlenklinik, Universitätsklinikum Rudolf Virchow, Freie Universität Berlin.
Der Radiologe
|November 1, 1993
Abstract:
The importance of neuroreceptor imaging in vivo using single photon emission tomography (SPECT) and positron emission tomography (PET) has increased enormously. The principal neurotransmitters, such as dopamine, GABA/benzodiazepine, acetylcholine, and serotonin, are presented with reference to anatomical, biochemical, and physiological features. The main radioligands for SPECT and PET are introduced, and methodological characteristics of both PET and SPECT are summarized. Finally, the results of neurotransmitter receptor imaging obtained so far will be discussed.