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Facilitation of social learning by treatment with an NMDA receptor antagonist
R Lederer1, E Radeke, C Mondadori
1Pharma Research Department, Ciba Ltd., Basel, Switzerland.
Behavioral and Neural Biology
|November 1, 1993
Abstract:
A single oral treatment with 0.3 mg/kg of the competitive NMDA receptor blocker CGP 37 849 improved the retention performance of rats in a social memory paradigm. The effect disappeared with increasing doses: at 1 mg/kg a positive trend could still be observed; at 3 mg/kg no effect whatever was detectable.