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Isolation and characterisation of five new anonymous X-specific probes. One of them detecting a TaqI RFLP
N Belhadj-Kacem1, S Heuertz, M C Hors-Cayla
1INSERM U12, Hôpital des Enfants-Malades, Paris, France.
Annales De Genetique
|January 1, 1993
Abstract:
The authors isolated five single-copy X-specific probes from an X-enriched library. These probes were regionally localized on the X chromosome by using somatic hybrid cell lines obtained from patients carrying different X-autosome translocations. Three clones were located between Xq23 and Xq26, the two others were mapped between Xp21 and Xp11.2. Analyses with different restriction enzymes indicated that one of them detects a TaqI polymorphism with a polymorphism information content (PIC) of 0.28.