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Localization of a N-ras-related sequence on rat chromosome 1
T Kunieda1, E Kobayashi, M Tachibana
1Imamichi Institute for Animal Reproduction, Ibaraki, Japan.
Abstract:
Location of the locus for a restriction fragment length polymorphism of N-ras-related sequences (NRAS2) on the rat chromosome 1 was determined by linkage analysis using a microsatellite locus (KAL) and a coat-color locus (C). The recombination frequencies between NRAS2 and C, NRAS2 and KAL, and C and KAL in 57 backcross progeny obtained from crosses of (WKS/Iar x IS/Iar) x WKS/Iar were 7.0 +/- 3.4%, 28 +/- 5.9%, and 23 +/- 5.6%, respectively. The order of the three loci on the rat chromosome 1 was determined as follows: KAL-C-NRAS2.