Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Progestin challenge test in postmenopausal patients

P Valenzuela1, R M Sabatel, V Valls

  • 1Department of Obstetrics and Gynecology, Hospital Universitario Principe de Asturias, Alcalá de Henares, Madrid, Spain.

International Journal of Gynaecology and Obstetrics: the Official Organ of the International Federation of Gynaecology and Obstetrics
|December 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Etiologic diagnosis of seasonal allergic rhinitis supported by artificial intelligence: The @IT-2020 project.

The Journal of allergy and clinical immunology·2026
Same author

EUFOREA summit in Brussels 2025: inspiring the future of allergy and respiratory care.

Frontiers in allergy·2026
Same author

Early Detection of Lower Adherence to Long-Term e-Diary Recording: A Checkpoint to Target Early Educational Intervention in Seasonal Allergic Rhinitis?

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2026
Same author

Traffic-related air pollution in utero modifies cytokine responses to stimuli of umbilical cord blood cells: a cohort study.

Environmental research·2026
Same author

Thiotepa, busulfan and fludarabine conditioning regimen for adult patients with lymphoid malignancies undergoing allogeneic stem cell transplantation: a study on behalf of GETH-TC.

Bone marrow transplantation·2025
Same author

High-resolution versus conventional manometry for the diagnosis of small bowel motor dysfunction.

Neurogastroenterology and motility·2024
Same journal

Letter to the editor: Anovulatory bleeding and the spectrum of bleeding disorders: Understanding heavy menstrual bleeding in adolescents.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics·2026
Same journal

Response to Letter to the Editor - anovulatory bleeding and the spectrum of bleeding disorders: Understanding heavy menstrual bleeding in adolescents.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics·2026
Same journal

Impact of Cell Saver technology on pro-hemostatic factors transfusion in placenta accreta spectrum interventions: A 10-year retrospective single-center study.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics·2026
Same journal

Beyond coverage: A dual-standard cascade and latent class analysis of maternal healthcare continuity in Ghana-Identifying who gets left behind and why.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics·2026
Same journal

Influence of class III obesity on mode of delivery and perinatal complications in nulliparous women: A matched case-control study.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics·2026
Same journal

Contraceptive implant discontinuation at one year in adults and adolescents: Implications for adolescent reproductive health services.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics·2026
See all related articles

The progestin challenge test identified postmenopausal women at higher risk for hormone-related endometrial cancer. Women who bled after the test were more overweight and had higher estradiol levels.

Area of Science:

  • Gynecology
  • Endocrinology
  • Oncology

Background:

  • Postmenopausal bleeding requires careful evaluation to rule out endometrial hyperplasia and cancer.
  • Hormonal factors, particularly estrogen, play a significant role in endometrial proliferation.

Purpose of the Study:

  • To analyze the clinical characteristics of postmenopausal women undergoing a progestin challenge test.
  • To identify predictors of endometrial response to progestin in this population.

Main Methods:

  • A progestin challenge test was administered to 157 postmenopausal women.
  • Characteristics of women who experienced withdrawal bleeding were compared to those who did not.

Main Results:

  • Withdrawal bleeding occurred in 14.01% of participants.

Related Experiment Videos

  • Women who bled were significantly more overweight, had higher plasma estradiol levels, and showed more superficial cells in vaginal smears.
  • Shorter duration of menopause was also associated with bleeding in the progestin test group.

    • Conclusions:

    • The progestin challenge test can identify postmenopausal women at increased risk for hormone-related endometrial pathology.
    • These findings suggest the test's utility in risk stratification for endometrial cancer.