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Potential biological targets for anti-Alzheimer drugs
H Allain1, S Belliard, J de Certaines
1Laboratoire de Pharmacologie, Faculté de Médecine, Hôpital Pontchaillou, Rennes, France.
Dementia (Basel, Switzerland)
|November 1, 1993
Abstract:
The stunning accumulation of data on the physiopathology of Alzheimer's disease is a real hinderance to pharmacologists who have to make decisions as to what molecules should be assessed first in man. Considering the cumbersomeness and cost of clinical trials in that field, a review of potential targets for drugs that are supposed to be active against the disease has become necessary, for a true definition of the rational justifications of trials to be envisaged.