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Lymphomatoid papulosis associated with acquired ichthyosis
R Yokote1, K Iwatsuki, H Hashizume
1Department of Dermatology, Hamamatsu University School of Medicine, Japan.
Journal of the American Academy of Dermatology
|May 1, 1994
Summary
This study reports a rare case of lymphomatoid papulosis co-occurring with acquired ichthyosis in a 64-year-old man. The findings suggest a shared pathomechanism between these conditions.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Lymphomatoid papulosis is a rare T-cell lymphoproliferative disorder.
- Acquired ichthyosis is a skin condition characterized by dry, scaling skin.
Observation:
- A 64-year-old male presented with papulonodular lesions and ichthyosiform eruption.
- Skin biopsies revealed atypical lymphocytes (CD3, CD4, Ki-1 positive) and features of ichthyosis vulgaris.
Findings:
- The patient exhibited lymphomatoid papulosis associated with acquired ichthyosis.
- While cell monoclonality was not definitively proven, a link is suggested.
Implications:
- Acquired ichthyosis may be triggered by lymphomatoid papulosis through a similar mechanism as other lymphoproliferative diseases.
- This case highlights a potential connection between cutaneous lymphomas and ichthyosis.