Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Clinical experience with minimal flow xenon anesthesia

H H Luttropp1, R Thomasson, S Dahm

  • 1Department of Anesthesia, University Hospital, Lund, Sweden.

Acta Anaesthesiologica Scandinavica
|February 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Contrasting risk patterns from human hunters and a large carnivore influence the habitat selection of shared prey.

Oecologia·2025
Same author

Hippocampal subfield volumes contribute to working memory interference control in aging: Evidence from longitudinal associations over 5 years.

Neuroimage. Reports·2025
Same author

Data of the Insect Biome Atlas: a metabarcoding survey of the terrestrial arthropods of Sweden and Madagascar.

Scientific data·2025
Same author

Age Differences in Brain Functional Connectivity Underlying Proactive Interference in Working Memory.

Human brain mapping·2025
Same author

Survival of Eurasian lynx in the human-dominated landscape of Europe.

Conservation biology : the journal of the Society for Conservation Biology·2025
Same author

Stepwise pathways from the olfactory cortex to central hub regions in the human brain.

Human brain mapping·2024

Xenon anesthesia offers potent anesthetic and analgesic effects, proving satisfactory in surgical patients. Despite its high cost, minimal flow systems make xenon administration feasible, though nitrogen accumulation requires management.

Area of Science:

  • Anesthesiology
  • Inorganic Chemistry

Background:

  • Xenon is a noble gas with demonstrated potent anesthetic and analgesic properties.
  • Its high manufacturing cost has historically limited its use as a general anesthetic.
  • Nitrous oxide is a commonly used anesthetic gas, but xenon offers superior potency.

Purpose of the Study:

  • To evaluate the feasibility and efficacy of xenon as a general anesthetic in a clinical setting.
  • To assess the anesthetic potential of xenon despite its high cost.
  • To investigate the administration of xenon using a minimal flow system.

Main Methods:

  • Seven ASA I-II patients undergoing elective surgery (cholecystectomy, hernia repair, mammoplasty) were studied.
  • Patients received propofol anesthesia followed by fentanyl-supplemented xenon anesthesia.

Related Experiment Videos

  • A minimal flow system maintained oxygen concentration at 30% during xenon administration.

    • Main Results:

    • Xenon anesthesia was administered for 76-228 minutes, with 8-14 liters of xenon used.
    • Anesthesia was satisfactory, and patients exhibited rapid recovery upon discontinuation of xenon.
    • The minimal flow system facilitated easy administration, but nitrogen accumulation was noted.

    Conclusions:

    • Xenon is a viable anesthetic agent, providing satisfactory anesthesia and rapid recovery.
    • Minimal flow xenon anesthesia is practical with automated systems.
    • The primary challenges for widespread xenon adoption include its high cost and potential for nitrogen accumulation.