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Bone reaction to subperiosteally implanted hydroxyapatite/collagen/glycosaminoglycans and coral in the guinea pig
C Alpaslan1, G Alpaslan, T Oygür
1Faculty of Dentistry, Gazi University, Ankara, Turkey.
Abstract:
Tissue reactions and new bone formation at 30, 60, and 90 days after the subperiosteal implantation of hydroxyapatite/collagen/glycosaminoglycans and blocks of coral in 18 guinea pigs were evaluated histologically with the use of polarized light and light microscopy. Animals implanted with coral showed new bone formation at each time interval and resorption of coral was observed. Histopathologic evaluation of hydroxyapatite/collagen/glycosaminoglycans implants revealed no evidence of new bone formation and the hydroxyapatite particles were surrounded by fibrous connective tissue.
