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Changes in brain neurotransmitters in rodent malaria
S Roy1, R N Chattopadhyay, S K Maitra
1Department of Physiology with Community Development, Vidyasagar University, Midnapore, India.
Indian Journal of Malariology
|December 1, 1993
Abstract:
Changes in brain neurotransmitters [5-hydroxytryptamine (5-HT), norepinephrine, histamine and dopamine] were studied in Plasmodium berghei-infected mice and rats. 5-HT and norepinephrine contents of brain decreased significantly in Plasmodium berghei-infected mice and rats, but histamine and dopamine contents remained unaltered. Decreased 5-HT and norepinephrine contents of brain may play a role in cerebral vasodilatation in malaria.