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A novel secretion apparatus for the assembly of adhesive bacterial pili
F Jacob-Dubuisson1, M Kuehn, S J Hultgren
1Dept of Molecular Microbiology, Washington University Medical School, Saint Louis, MO 63110-1093.
Trends in Microbiology
|May 1, 1993
Abstract:
The biogenesis of most types of bacterial pili requires two specialized proteins: a chaperone that caps the pilus subunits in the periplasm, and an outer membrane usher that receives the subunits and serves as an assembly platform. This secretion and assembly machinery is proposed to be a novel export apparatus found widely in Gram-negative pathogens.