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Mapping the sheep genome: practice, progress and promise

T E Broad1, D F Hill

  • 1Gene Mapping Unit, AgResearch Grasslands Centre, Palmerston North, New Zealand.

The British Veterinary Journal
|May 1, 1994
PubMed
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Sheep genome mapping is accelerating, with over 100 loci identified. This progress in DNA technologies and genetics aids in identifying genes for important traits and improving sheep breeds through marker-assisted selection.

Area of Science:

  • Genomics
  • Animal Genetics

Background:

  • Significant advancements in DNA technologies and genetics have accelerated sheep gene mapping.
  • Over 100 loci have been mapped on the sheep genome, doubling the number from three years prior.

Purpose of the Study:

  • To review strategies and methods for sheep gene mapping.
  • To highlight the utility of comparative genome analysis in this process.
  • To describe the ongoing sheep genome mapping project.

Main Methods:

  • Utilizing advancements in DNA technologies and genetics.
  • Employing comparative genome analysis.
  • Describing ongoing gene mapping projects.

Main Results:

  • The rate of sheep gene mapping is increasing rapidly.

Related Experiment Videos

  • Over 100 loci are now mapped on the sheep genome.
  • Identification of genes for important traits is becoming more feasible.

    • Conclusions:

    • Accelerated gene mapping will elucidate the biological basis of important sheep traits.
    • This research facilitates genetic improvement of sheep and product quality via marker-assisted selection.
    • Applications include disease understanding, treatment, and breeding tools.