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Recurrent generalized lichen nitidus associated with amenorrhea

S Taniguchi¹, M Chanoki, T Hamada

¹Department of Dermatology, Osaka City University Medical School, Japan.

Acta Dermato-Venereologica

|May 1, 1994

Summary

Recurrent lichen nitidus eruptions linked to the menstrual cycle improved with hormone therapy. This suggests hormonal factors may influence lichenoid tissue reactions in this condition.

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Area of Science:

Dermatology
Endocrinology

Background:

Lichen nitidus is a rare, benign skin condition characterized by small, pinpoint papules.
Recurrent generalized lichen nitidus presents a diagnostic and therapeutic challenge.

Observation:

A patient presented with recurrent generalized lichen nitidus eruptions.
The skin lesions correlated with the proliferative phase of the menstrual cycle.

Findings:

Hormone replacement therapy, specifically estrogen and progesterone for amenorrhea, led to significant improvement in the lichen nitidus lesions.
This clinical response suggests a potential role for hormonal fluctuations in the disease's pathogenesis.

Implications:

Hormonal modulation may be a therapeutic consideration for select cases of recurrent lichen nitidus.

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Further research is warranted to elucidate the precise mechanisms linking hormonal factors to lichenoid tissue reactions.