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Doppler enhancement with SH U 508A in multiple vascular regions
K Q Schwarz1, H Becher, C Schimpfky
1Cardiology Unit, University of Rochester Medical Center, NY 14642.
Radiology
|October 1, 1994
Summary
Intravenous contrast agent SH U 508A significantly enhances cardiac and peripheral vascular Doppler signals. This contrast enhancement improves diagnostic confidence in suboptimal Doppler examinations.
Area of Science:
- Cardiovascular Imaging
- Medical Ultrasound
- Pharmacology
Background:
- Doppler ultrasound is crucial for assessing blood flow.
- Suboptimal signal intensity can limit diagnostic accuracy.
- Contrast agents can improve ultrasound imaging quality.
Purpose of the Study:
- To evaluate the effectiveness of SH U 508A.
- To quantify Doppler signal enhancement in vascular and cardiac applications.
- To determine the duration of the contrast effect.
Main Methods:
- Intravenous bolus injections of SH U 508A were administered to 30 patients.
- Doppler signal intensity was measured in suboptimal examinations.
- Contrast effect duration and signal enhancement magnitude were recorded.
Main Results:
- SH U 508A demonstrated no adverse effects.
- Doppler signal intensity increased by over 16 dB in all regions.
- Diagnostic confidence improved from 35% to 91% post-enhancement.
- The contrast effect persisted for over 120 seconds.
Conclusions:
- SH U 508A effectively enhances cardiac, femoral, and cerebral arterial Doppler signals.
- The agent improves diagnostic confidence in challenging Doppler studies.
- SH U 508A is a valuable tool for vascular and cardiac ultrasound.