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Characterization of a cDNA encoding the beta-chain of baboon receptor glycoprotein GPIb
1Division of Cardiology, Emory University School of Medicine, Atlanta, GA 30322.
Gene
|May 30, 1993
Abstract:
A cDNA probe, encoding part of the baboon integrin polypeptide, GPIIb, was used to screen a cDNA library derived from baboon platelet polyadenylated mRNA. One cross-hybridizing clone was found to be 94% similar to a human cDNA encoding the beta-chain of the receptor for von Willebrand factor, a major component of the platelet-subendothelium attachment mechanism.