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Choroid plexus papillomas

R Sharma1, D Rout, A K Gupta

  • 1Department of Neurosurgery, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India.

British Journal of Neurosurgery
|January 1, 1994
PubMed
Summary
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Choroid plexus papillomas (CPPs) are rare brain tumors. Complete surgical removal offers the best outcome for patients with these rare neoplasms.

Area of Science:

  • Neurosurgery
  • Oncology
  • Neuropathology

Background:

  • Choroid plexus papillomas (CPPs) are rare intracranial neoplasms, comprising less than 1% of all brain tumors.
  • These tumors most commonly occur in the fourth ventricle in adults, but posterior fossa locations were noted more frequently in children in this series.

Purpose of the Study:

  • To present the clinical experience with 13 consecutive cases of choroid plexus papillomas.
  • To analyze the management, outcomes, and optimal surgical approach for CPPs.

Main Methods:

  • Retrospective review of 13 patients (8 children, 5 adults) managed between 1981 and 1991.
  • All patients underwent surgical tumor resection, with histological confirmation.
  • Tumor location, extent of resection, and patient outcomes were analyzed.

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Main Results:

  • Tumors were located in the fourth ventricle (5), lateral ventricle (4), third ventricle (1), cerebellomedullary cistern (2), and cerebellopontine angle (1).
  • Total tumor excision was achieved in 9 patients, with subtotal excision in 4.
  • Two surgical mortalities occurred early in the series. Nine patients are doing well with follow-up ranging from 9 to 90 months.

Conclusions:

  • Surgical resection aiming for total excision should be the primary treatment strategy for choroid plexus papillomas.
  • While the fourth ventricle is a common site, posterior fossa locations can occur, even in pediatric patients.