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[Alrheumum in the daily practice]

E Winkler

    Fortschritte Der Medizin
    |November 11, 1976
    PubMed
    Summary

    The new antirheumatic drug Ketoprofen (Alrheumun) demonstrated good activity and tolerance in 100 outpatients with inflammatory conditions. Most patients experienced no side effects, with minimal treatment interruptions due to adverse events.

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    Area of Science:

    • Rheumatology
    • Pharmacology

    Background:

    • Rheumatoid arthritis, osteoarthrosis, and soft tissue conditions are prevalent musculoskeletal disorders.
    • Effective and well-tolerated antirheumatic drugs are crucial for managing these conditions.

    Purpose of the Study:

    • To evaluate the clinical activity and tolerance of Ketoprofen (Alrheumun) in an open-label trial.
    • To assess the drug's efficacy in common rheumatic and soft tissue conditions under practice conditions.

    Main Methods:

    • An open trial involving 100 outpatients with rheumatoid arthritis, osteoarthrosis, or soft tissue conditions.
    • Daily administration of 3 capsules of Alrheumun.
    • Evaluation of drug activity and tolerance, including monitoring for side effects and laboratory tests.

    Main Results:

    • Ketoprofen (Alrheumun) showed good activity in patients across all treated conditions.
    • A high tolerance rate was observed, with 80% of patients experiencing no side effects.
    • Treatment interruption due to side effects occurred in only two patients.
    • No negative influence on laboratory test results was detected.

    Conclusions:

    • Ketoprofen (Alrheumun) is an effective and well-tolerated option for managing rheumatoid arthritis, osteoarthrosis, and soft tissue conditions.
    • The drug exhibits a favorable safety profile with minimal adverse events in a real-world clinical setting.

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