Reinvestigation of lipid peroxidation of linolenic acid

Recently, we deduced a mechanism for lipid peroxidation of linoleic acid [1]. This mechanism was now applied to predict the occurrence of previously unknown lipid peroxidation products of linolenic acid. The proposed structures of peroxidation products allowed to search for these predicted compounds in reaction mixtures with the aid of 'ion trace' by mass spectrometry. Thus, a great number of previously unknown lipid peroxidation products was detected. It is assumed that these compounds also occur--at least as intermediates--in lipid peroxidation processes in mammalian tissue.