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Gastric carcinoma, an endoscopically curable disease
M A Fujino1, A Morozumi, Y Kojima
1First Department of Medicine, Yamanashi Medical University, Japan.
Summary
Endoscopic mucosal resection (EMR) offers a curative treatment for early gastric carcinoma. This technique is effective for intramucosal adenocarcinoma within specific size and differentiation criteria, with follow-up ensuring no recurrence.
Area of Science:
- Gastroenterology
- Oncology
- Endoscopic Surgery
Background:
- Refined endoscopic diagnosis has established 'early gastric carcinoma' and its features.
- Endoscopic mucosal resection (EMR), laser therapy, and endoscopic-endosonography enable curative treatment for intramucosal gastric cancer.
Purpose of the Study:
- To define the indications for endoscopic treatment of gastric carcinoma.
- To outline the preferred endoscopic treatment procedures and follow-up strategies for early gastric cancer.
Main Methods:
- Analysis of lymphatic metastasis to define endoscopic treatment indications.
- Endoscopic mucosal resection (EMR) as the preferred treatment modality.
- Histological examination of resected specimens to ensure complete resection.
Main Results:
- Established indications for endoscopic treatment include specific types of intramucosal adenocarcinoma based on lesion characteristics and differentiation.
- EMR is the primary endoscopic treatment, supplemented by repeat EMR, laser therapy, or surgery if needed.
- Periodic endoscopic follow-up is crucial for detecting residual cancer or recurrence.
Conclusions:
- Early gastric carcinoma is endoscopically curable.
- EMR provides a safe and effective treatment option for selected intramucosal gastric cancers.
- Careful patient selection and follow-up are essential for successful endoscopic management.