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Updated: Aug 11, 2026

Technical Demonstration of Whole Genome Array Comparative Genomic Hybridization
Published on: August 5, 2008
Genome scanning methods
1Stanford University School of Medicine, Howard Hughes Medical Institute, California 94305-5428.
Abstract:
Recently introduced methods can allow an entire genome to be scanned at one time for sequences linked to trait loci. Representational difference analysis and genomic mismatch scanning are designed, respectively, to isolate and map sequences that differ between genomes discordant for a trait, or that are identical between genomes concordant for a trait. Other methods allow the whole genome to be scanned for regions of increased or decreased copy number, or for differentially methylated sequences.
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