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Bone marrow transplantation in Thailand
1Department of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Bone Marrow Transplantation
|June 1, 1994
Summary
Bone marrow transplantation effectively treats aplastic anemia, thalassemia, leukemia, and lymphoma in Thailand. Outcomes are better for non-malignant conditions, with low rates of graft-versus-host disease and CMV infection, despite challenges.
Area of Science:
- Hematology
- Transplantation Medicine
- Oncology
Background:
- Prevalence of aplastic anemia, thalassemia, leukemia, and lymphoma in Thailand.
- Bone marrow transplantation as a curative option for these hematologic disorders.
Purpose of the Study:
- To evaluate the outcomes of bone marrow transplantation in Thailand.
- To assess the efficacy and challenges of bone marrow transplantation for malignant and non-malignant hematologic diseases.
Main Methods:
- Review of bone marrow transplantation procedures and outcomes in Thailand.
- Analysis of success rates in non-malignant versus malignant hematologic conditions.
- Assessment of complication rates, including graft-versus-host disease (GVHD) and cytomegalovirus (CMV) infection.
Main Results:
- Bone marrow transplantation shows favorable results in non-malignant diseases compared to hematological malignancies.
- Low incidence of graft-versus-host disease (GVHD) and cytomegalovirus (CMV) infection observed.
- Challenges include personnel shortages, limited facilities, and high costs.
Conclusions:
- Bone marrow transplantation is a viable treatment for prevalent hematologic disorders in Thailand.
- While successful, particularly for non-malignant conditions, challenges in resources and cost require attention.
- Further development is needed to overcome existing limitations and improve accessibility.