Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bone marrow transplantation in Malaysia

H P Lin1, L L Chan, A Tan

  • 1Department of Paediatrics, Faculty of Medicine University of Malaya, Kuala Lumpur, Malaysia.

Bone Marrow Transplantation
|June 1, 1994
PubMed
Summary

Malaysia

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparative real-world analysis of stereotactic body radiotherapy versus conventional radiotherapy for Chinese patients with low- to intermediate-risk localised prostate cancer.

Hong Kong medical journal = Xianggang yi xue za zhi·2026
Same author

Response to recent technical tip describing screw length measurement technique.

Annals of the Royal College of Surgeons of England·2026
Same author

Recent advancements in radiotherapy for hepatocellular carcinoma.

ESMO gastrointestinal oncology·2026
Same author

Real-world treatment outcomes for pancreatic neuroendocrine tumours: a single tertiary referral institute experience.

ESMO gastrointestinal oncology·2026
Same author

Neoadjuvant immunotherapy for early-stage hepatocellular carcinoma: the arts and science.

ESMO gastrointestinal oncology·2026
Same author

Variation in mortality following hip fracture across the Asia Pacific region: Systematic review and proportional meta-analysis.

Archives of gerontology and geriatrics·2024

Area of Science:

  • Pediatric Hematology Oncology
  • Transplantation Immunology

Background:

  • The only Bone Marrow Transplant (BMT) center in Malaysia exclusively serves pediatric patients.
  • Since 1987, the center has performed 89 BMTs utilizing reverse barrier nursing techniques.

Purpose of the Study:

  • To evaluate the efficacy and cost-effectiveness of a pediatric Bone Marrow Transplant (BMT) program in Malaysia.
  • To compare outcomes, including survival rates, infection rates, and graft-versus-host disease (GVHD), with international standards.

Main Methods:

  • Retrospective analysis of 89 pediatric BMT cases performed between 1987 and the present.
  • Application of reverse barrier nursing techniques throughout the study period.
  • Data collection on survival rates, infection complications, GVHD, interstitial pneumonitis, and transplant costs.

Main Results:

  • An overall survival rate of 73% was achieved, with most survivors leading normal lives.
  • Early and late infection rates were 46% and 13%, respectively, comparable to international benchmarks.
  • Graft-versus-host disease (GVHD) and interstitial pneumonitis were less frequent and severe compared to Western centers.
  • Early septicemia occurred in 36% of cases, with an immediate mortality rate below 10%.

Conclusions:

  • The Malaysian pediatric BMT program demonstrates favorable outcomes, including high survival rates and manageable complication rates.
  • The program is cost-effective, with an average cost of US $8000 per transplant, significantly lower than overseas options.
  • The established BMT program is simple, effective, and economically viable for pediatric patients in Malaysia.

Related Experiment Videos