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Bone marrow transplantation in India

S H Advani¹, T Saikia

¹Department of Medical Oncology, Tata Memorial Hospital, Bombay, India.

Bone Marrow Transplantation

|June 1, 1994

Summary

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Bone marrow transplantation (BMT) in India shows promising survival rates for thalassemia major (90%) and encouraging results for acute myeloid leukemia and aplastic anemia (50%). However, outcomes for chronic myeloid leukemia remain poor, necessitating BMT facility expansion.

Area of Science:

Hematology
Transplant Medicine
Oncology

Background:

Bone marrow transplantation (BMT) facilities in India have experienced gradual development since 1983.
The establishment and growth of BMT services are critical for managing various hematological disorders.

Purpose of the Study:

To evaluate the current status and outcomes of bone marrow transplantation in India.
To identify areas of success and challenges in BMT services across the country.

Main Methods:

Retrospective analysis of BMT cases and facility growth in India.
Survival data analysis for different hematological conditions treated with BMT.

Main Results:

Disease-free survival rates of approximately 50% for acute myeloid leukemia and aplastic anemia.

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A high survival rate of 90% for thalassemia major.

Consistently poor outcomes reported for chronic myeloid leukemia patients undergoing BMT.

Conclusions:

BMT in India has demonstrated significant success in specific conditions like thalassemia major.
The current BMT infrastructure requires expansion to meet the growing demand and improve patient outcomes.
Further research and development are needed to address the challenges in treating chronic myeloid leukemia with BMT.